Increased FNDC5 is associated with insulin resistance in high fat-fed mice
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Increased FNDC5 is associated with insulin resistance in high fat‐fed mice
FNDC5/irisin, has recently been identified as a novel protein that stimulates the "browning" of white adipose by inducing thermogenesis via increased uncoupling protein 1 (UCP1). We tested the hypothesis that high fat diet-induced prediabetic mice would exhibit increased FNDC5 and this effect would be attenuated by chronic exercise. C57BL/6 mice were randomized into three groups for the 4 week ...
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ژورنال
عنوان ژورنال: Physiological Reports
سال: 2017
ISSN: 2051-817X
DOI: 10.14814/phy2.13319